βk-2C-B is a synthetic drug, more precisely it is the beta-keto analogue of the controlled substance 2C-B (2,5-dimethoxy-4-bromophenethylamine), synthesized for the first time by Alexander Shulgin. It is not known who first synthesized βk-2C-B, but it appeared on the market as a recreational drug in mid-2013.  In the following years, several articles were published that reported analytical characterizations of the substance.  It is offered online and is called a psychedelic drug. Effective October 12, 2016, βk-2C-B has become a controlled substance in Canada (Schedule III).  It is also illegal in Germany, Switzerland and the United Kingdom. Bath salts drug street name of many RC opiates and street psychedelic drugs to buy only the legal list of high drugs and the legality RC (US Controlled Substances List, what are Schedule 4 drugs, Schedule 1-7 drugs) Our company supplies beta-keto 2C-B to the EU, UK, Germany, Ireland, France, Germany, the Netherlands, Amsterdam and other parts of the world. To buy beta-keto 2C-B EU online, you must first claim legality in your country of residence. βk-2C-B is illegal in Switzerland, Sweden and UK Find out what bk-2CB is, bk-2CB is legal, beta-keto 2C-B effects, dosage of the product and many other facts related to the experience on the crystals site for sale. If you have never tested this chemical before, we recommend that you do a drug test and then place a full order for products. The substance represents a synthetic drug of psychedelics and their effects are similar to those of 2C-B and BOB. βk-2C-B has received more attention since 2013, when the first testimonials appeared on the Internet after it appeared on the market for research chemicals on “online stores” selling it as a “legal substitute for 2C-B”.  Researchers and laboratory staff who need the drug bk-2CB in their tests are in exactly the right place. Our American company RC supplies Beta-Keto 2C-B research chemicals directly from China. The product is in stock and has perfect quality thanks to the production process with modern technologies. There is a strong similarity between the subjective effects caused by βk-2C-B and 2C-B. However, βk-2C-B is often described as more stimulating and less psychedelic. This, combined with its long duration, could increase the perceived severity of the effects. Physiological stress could also result from βk-2C-B. Indeed, as with 2C-B, an increase in heart rate and an increase in blood pressure are often reported. This could further potentiate the perceived feeling of euphoria, perception (i.e. the intensity of color) and bodily sensations. Great prices and fast shipping. I had never used a research chemical store outside of Canada, but this is the real deal. Thank you! Tolerance to the effects of βk-2C-B accumulates almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to return to the baseline (in the absence of additional consumption). Bk-2C-B represents cross-tolerance with all psychedelics, which means that after consuming βk-2C-B, all psychedelics have a reduced effect. If you would like to see NMR results for bk-2C-B HCL or any other chemical, please email us at email@example.com. βk-2C-B (Bk-2C-B; 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)ethane1-one) is a novel psychedelic substance. It is the analogue of the beta (β) ketone structure of 2C-B, a psychedelic drug of the 2C family. It is used as a recreational drug that is usually taken orally. βk-2C-B is a controlled substance in Canada, Germany, Switzerland and the United Kingdom. In contrast, βk-2C-B has a relatively high dose compared to members of the 2C family. This suggests that affinities for pharmacologically active centers differ significantly between these compounds. Qualitatively, however, the effects of this higher dose are similar, which could lead to higher toxicity. In addition, its longer half-life would increase exposure to certain sites in the body, which could lead to an increase in the toxic response of βk-2C-B compared to 2C-B. As with compounds of the 2C family, species differentiation for βk-2C-B metabolism is likely. Indeed, the enzymatic expressions of biotransformation enzymes can differ considerably depending on the species and sex. A long-acting, empathogenic psychedelic with unpredictable efficacy. About twice as long as 2c-b. Inactivated by a high pH. The primary amine of βk-2c-b can react with the betaketone of a second molecule of βk-2C-B and vice versa to form two imin bonds between the two molecules. Water is removed in this reversible reaction. However, the process of imin formation depends on pH and is usually the most important near pH of 5. At high pH, there is not enough acid to protonate the hydroxyl group, while at low pH, most of the amine reagent is protonated and therefore loses its nucleophilia, which is a prerequisite for the reaction. Although imin formation is preferred in slightly acidic environments, there is experimental evidence that the intramolecular reaction to βk-2c-b is mild at neutral pH. When imin formation is fully present between two molecules of βk-2C-B, a purple pyrazine dimer is formed. The dimer can be converted back to βk-2C-B by iminhydrolysis: a process in which acid catalysis is possible, but not an absolute prerequisite. Taking into account the chemical structure of βk-2C-B, various possible interactions between the compound and target receptors can take place in the body. Functional groups within the structure perform pharmacological activity at the receptor sites. The most notable structure-activity relationships (DAS) for βk-2C-B are hydrogen bonds, dipole-dipole interactions, Van der Waals interactions, and the polar hydrophobic nature of the bromine atom. For βk-2C-B, four different SARs are offered: On the website, the following information is available to visitors interested in rc: Subjective effects include open and closed eyes, time distortion, euphoria and self-loss. Compared to 2C-B, its effects are often described as much more stimulating and less psychedelic with a significantly longer duration. βk-2C-B (beta-Keto 2C-B, bk-2C-B) is a psychedelic drug structurally related to 2C-B and BOB and sold online as a synthetic drug.  It has been found to be a polymorph and, under basic to neutral conditions, tends to self-condensation, which forms a dimer, similar to the reaction involved in pyrazine synthesis.  Not much is known about the pharmacokinetics of βk-2C-B as it is a new psychedelic. The clearance and biotransformation of the compound in the body is therefore difficult to interpret. In addition, an assessment of the toxicity caused by βk-2C-B is not possible based on the current state of research on this compound. This is common with many synthetic drugs and therefore recreational use is poorly advised. Very few data are available on the pharmacological properties, metabolism and toxicity of Bk-2C-B. As a result, users are advised to approach this new hallucinogenic substance and misunderstand it with the right amount of precautions and harm reduction practices if you want to use it. No hazards have been reported specifically for βk-2C-B, but some common hazardous effects may be present in 2C phenethylamines that may be present for βk-2C-B. These include chills, nausea, anxiety, confusion, restlessness, high blood pressure, seizures, and death. The use of βk-2C-B can lead to hallucinations and violence, as well as disordination; These could have serious consequences, not only for the user, but also for the general public. The severity of such effects depends on the dosage, with the risk increasing at higher doses. Both the United States and the United Kingdom have reported non-fatal and fatal 2C-phenethylamine poisoning and substitutions of this family of psychoactive substances. The original synthesis of βk-2C-B is not available in the public archives. However, based on information from internet forums and scientific studies, it appears that it was not originally synthesized in the 1970s by Alexander Shulgin as many 2C-x compounds. Overall, βk-2c-b is considered a relatively obscure substance, even among research chemicals.   An analysis of Google search history between 2013 and 2017 shows that 2C-B was searched 3 to 4 times more often βk-2C-B.  Since 2017, βk-2C-B seems to have almost completely disappeared from the free market. As with other new psychedelics, βk-2C-B is readily available online as it is not regulated in most countries. In general, it is listed online as a psychedelic substance available “for research purposes only” and “not for human consumption.” The target market listed is often intended for in vitro purposes only. Bk-2C-B probably acts as a partial agonist of 5-HT2A of the “mixed taste”. The effect is believed to stem from its effectiveness on 5-HT2A receptors. However, the role of these interactions and how they lead to psychedelic experiences remain elusive. However, extrapolation from its parent compound is possible, but not conclusive. In general, compounds of the 2C family have been shown to be metabolized by hepatic hepatocytes, resulting in deamination and demethylation. Oxidative deamination is common and substitutes for dimethoxybenzoic acid can be produced in this way of biotransformation. Additional metabolism can be performed by demethylation. The first reliable mention of βk-2C-B did not appear until 2004, although it played only a minor role in a scientific study as a precursor of serotonin receptor agonists 5-HT2A.  The next confirmed statement of the substance may be dated December 2007.